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What are NADH and NAD+?

Feb 25

Take into consideration the following three points while reading on to learn the fundamentals of the NAD and NADH definition:


  • Both NADH and NAD+ are referred to as NAD in this context.
  • The energy-producing role of NAD is critical, as it fuels your genes for extended life.
  • As you become older, your NAD levels gradually decline, but options are available to help!


What is NAD+?

NAD is an abbreviation for nicotinamide adenine dinucleotide, referred to as NAD+ or NAD in some contexts. For the uninitiated, NAD is a critical coenzyme generated by the body and discovered throughout every cell of the body. Numerous metabolic mechanisms, the most noteworthy of which is cellular repair, are influenced by the presence of NAD+. Increased NAD levels are associated with advancing age, and that is when the body is subjected to metabolic stress, as in when exposed to a virus.


NADH and NAD+ are two distinct types of NAD. Chemically, those two types are highly similar, although they are not precise duplicates. Even though NAD can sometimes be called just NAD (as in the example above), the plus sign is crucial since NAD pertains to the two forms together.


We'll go over the variations between NADH and NAD+ and how the two forms interact with one another in our bodies in the sections below.


What does NAD+ Do?

NAD is involved in two different kinds of reactions in the body system. First and foremost, NAD+ aids in the conversion of the nutrients we consume into energy, which will then be utilized in cellular metabolic processes. Second, NAD functions as a molecule that assists proteins in regulating other cellular functions. 


What is NADH?

The following is the definition of NADH: hydrogen (H) + nicotinamide adenine dinucleotide (NAD).


What is the difference between this and NAD+? To put it another way, NADH and NAD+ exist together as what is known as a "redox couple." The oxidized form of NAD+ is NAD+, and the reduced form of NAD+ is NADH.


NADH and NAD+ 

NADH and NAD+ have distinct roles to play in the body. When it comes to the importance of NADH to NAD+ in the body, the jury is still out.


Here's what we've learned so far while the study continues to verify the information presented above:


NAD+ in our bodies is finite and diminishes as we grow older. NAD+, as previously stated, is essential for a wide range of biological activities, including sirtuins, a group of proteins, to ensure that our metabolism remains healthy and our cells can produce energy, as well. Because of the body's usage of NADH and NAD+ molecules and the inevitable reduction of NAD+ with age, our ratio is pushed further lower as NADH rises.


The necessity of maintaining a healthy NADH to NAD+ ratio will become more apparent as more studies are completed. Still, for the time being, we do know that raising the quantity of NAD+ in our bodies is critical for slowing down the aging process and age-related disorders.